Scientific Literature
Pregnancy and Childbirth in Women With Thalassemia: Past And Present
Demurtas, A., Gianesin, B., Zappu, A., Cassinerio, E., Leoni, S., Ricchi, P. & Origa, R. Haematologica, 111(1), 392. (2025)
This is a multicenter retrospective study (26 Italian centers) supported by the Italian Society of Thalassemia and Hemoglobinopathies (SITE) to assess how the advances of the last decades have affected pregnancy outcomes in transfusion-dependent beta-thalassemia (β-TDT) women (N=251, 346 pregnancies) and their newborns during the period 1992-2024 (Online Supplementary Table S1).
The study was approved by the Ethics Committee of the participating centers, registered with clinicalTrials.gov (clinicaltrials .gov identifier: NCT06889727; Observational Studies Register – AIFA: 1817), and conducted in accordance with Good Clinical Practice guidelines and the Declaration of Helsinki.
Written informed consent was obtained from all patients.
