Pregnancy
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Scientific Literature
EHA Recommendations for Preconceptual and Antenatal Screening and Prenatal Diagnosis for Hemoglobinopathies
Abstract Thalassemia and sickle cell disease (SCD) are among the most common monogenic disorders worldwide. They cause chronic hemolytic anemia, the consequences and prognosis of which vary considerably depending on…
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Scientific Literature
Addressing Obstetric and Gynecologic Needs in Thalassemia
Abstract Thalassemia represents a spectrum of rare, inherited blood disorders associated with a range of disease- and treatment-related complications. Thalassemia can have a significant effect on the female reproductive system,…
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Scientific Literature
β-Thalassemia Minor Is Associated With High Rates of Worsening Anemia in Pregnancy
Worsening of anemia because of β-thalassemia minor in pregnancy is not a well-known complication and, when acknowledged, is described as being limited to mild anemia. Knowing that individuals with β-thalassemia…
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Scientific Literature
Pregnancy and Childbirth in Women With Thalassemia: Past And Present
This is a multicenter retrospective study (26 Italian centers) supported by the Italian Society of Thalassemia and Hemoglobinopathies (SITE) to assess how the advances of the last decades have affected…
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Scientific Literature
The Impact of Various Types of Α-Thalassemia οn Perinatal Complications and Pregnancy Outcomes in Pregnant Women
Abstract This study aims to investigate the adverse effects of different types of α-thalassemia on pregnant women and their differences, so as to provide a reference for the prevention and…
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Scientific News
WHO Issues First Global Guideline on Sickle Cell Disease in Pregnancy
Why This Matters High maternal risk: Pregnant women with SCD face a 4–11× greater risk of maternal mortality and elevated rates of pre-eclampsia, while their infants are at increased…
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News
THE HIDDEN RISK | Worsening Anaemia Linked to Pregnancy in Individuals with β-Thalassaemia Minor
β-thalassaemia minor is a genetic blood disorder that typically causes mild anaemia which typically does not require medical treatment. However, this study suggests that pregnant women with this condition may…
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Scientific Literature
Pregnancy, Delivery, and Neonatal Outcomes Among Women With Beta-Thalassemia Major: A Population-Based Study of a Large US Database
Abstract Purpose: We explored the effect of beta-thalassemia major on pregnancy and delivery outcomes in a non-endemic area, utilizing the USA population database. Methods: This is a retrospective study utilizing…
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Scientific Literature
Guideline for the Management of Conception and Pregnancy in Thalassaemia Syndromes: A British Society for Haematology Guideline
This comprehensive guideline, developed by a representative group of UK-based medical experts specialising in haemoglobinopathies, addresses the management of conception and pregnancy in patients with thalassaemia. A systematic search of…
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Scientific Literature
Pregnancy Outcomes and Iron Status in β-Thalassemia Major and Intermedia: A Systematic Review and Meta-analysis
Advancements in orally bioavailable iron chelators and MRI methods have improved life expectancy and reproductive potential in Thalassemia Major (TM) and Thalassemia Intermedia(TI). Pregnancy is associated with adverse maternal and…
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