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Scientific Literature

Addressing Obstetric and Gynecologic Needs in Thalassemia

Vlachodimitropoulou, E., Baldini, M., Al-Samkari, H., Cappellini, M. D., Coates, T. D., Kuo, K. H., & Musallam, K. M. O&G Open, 3(4), e181. (2026)

Abstract

Thalassemia represents a spectrum of rare, inherited blood disorders associated with a range of disease- and treatment-related complications.

Thalassemia can have a significant effect on the female reproductive system, and obstetrics and gynecology specialists have a key role to play in managing the disease as part of a multidisciplinary team.

Here, we review the role of obstetrics and gynecology specialists in thalassemia from puberty to pregnancy and postnatal support, including diagnosis and management of complications, supporting patients through pubertal and fertility issues, and the risks associated with pregnancy.

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