Renal Complications

Dapagliflozin in Patients with Homozygous β-Thalassemia and Albuminuria

Abstract Patients with homozygous β-thalassemia show continuously improved survival, which has contributed to the development of kidney complications, predominantly expressed as increased albuminuria. In particular, patients with transfusion-dependent thalassemia (TDT)…

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Management of Kidney Disease with Sickle Cell Disease

Abstract: Sickle cell disease is the most common inherited blood cell disorder in the United States. Vaso-occlusion and hemolysis are hallmark features of sickle cell disease that may lead to…

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Renal Findings in Patients with Thalassemia at Abdominal Ultrasound: Should We Still Talk about “Incidentalomas”? Results of a Long-Term Follow-Up

Abstract We retrospectively collected all ultrasound imaging data of our thalassemia patients over a period of 10 years with the aim of assessing the prevalence and the risk factors of…

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Early Detection of Renal Complication in Children With Sickle Cell Disease: A Single Center Prospective Study

Introduction: This observational cross-sectional study aimed to identify predictors of renal complications in pediatric patients with sickle cell disease (SCD) at King Salman Armed Forces Hospital, Tabuk, Saudi Arabia, over…

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Renal Dysfunction in Pediatric Patients in Iraq With β-Thalassemia Major and Intermedia

Background: With optimum transfusion and chelation therapy, the survival of β-thalassemia patients and the incidence of various complications, including renal complications, have improved. Objectives: To investigate renal involvement in β-thalassemia…

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Frequency, Pattern, and Associations of Renal Iron Accumulation in Sickle/β-Thalassemia Patients

We evaluated frequency, pattern, and associations of renal iron accumulation in sickle/β-thalassemia. Thirty-three sickle/β-thalassemia patients (36.5 ± 14.7 years; 13 females), 14 homozygous sickle cell disease (SCD) patients, and 71 thalassemia major (TM)…

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Kidney Stones in Transfusion-Dependent Thalassemia: Prevalence and Risk Factors

As patients with transfusion-dependent thalassemia (TDT) are living longer, novel morbidities are being recognized. The purpose of this review is to summarize the current knowledge regarding the prevalence and risk…

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Renal Function in β-Thalassemia Major Patients Treated with Two Different Iron-Chelation Regimes

Background Renal injury in transfusion dependent β thalassemia patients (TDT) has been attributed to iron overload, chronic anemia and iron-chelation therapy (ICT) toxicity. We studied renal function in TDT patients…

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Assessment of Subclinical Renal Glomerular and Tubular Dysfunction in Children with Beta Thalassemia Major

Background: A good survival rate among patients with beta thalassemia major (beta-TM) has led to the appearance of an unrecognized renal disease. Therefore, we aimed to assess the role of…

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