Catherine Skari

Update in Laboratory Diagnosis of Thalassemia

Alpha- and β-thalassemias and abnormal hemoglobin (Hb) are common in tropical countries. These abnormal globin genes in different combinations lead…

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Sickle Cell Pain Crisis: Clinical Guidelines for the Use of Oxygen

Nocturnal hypoxemia is a prelude to vaso‐occlusive crisis (VOC). Vascular occlusion and disruption of tissue oxygenation are a prequel to…

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Editing a γ-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes

Sickle cell disease (SCD) is caused by a single amino acid change in the adult hemoglobin (Hb) β-chain that causes…

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Management of Age-associated Medical Complications in Patients with β-Thalassemia

Introduction: β-Thalassemia syndromes are among the most common monogenic disorders worldwide. Clinically, on the basis of the severity of the…

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Innovative Curative Treatment of Beta-Thalassemia: Cost-efficacy Analysis of Gene Therapy Versus Allogenic Hematopoietic Stem Cell Transplantation

Seventy-five percent of patients with beta thalassemia (β-thalassemia) do not have human leukocyte antigen–matched siblings and until recently had no…

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Need for a Universal Thalassemia Screening Programme in India? A Public Health Perspective

Thalassemia is one of the significant public health concerns as the carrier rate and disease numbers are increasing worldwide. The…

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Hepatocellular Carcinoma in β-Thalassemia Patients: Review of the Literature with Molecular Insight into Liver Carcinogenesis

With the continuing progress in managing patients with thalassemia, especially in the setting of iron overload and iron chelation, the…

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Nutritional Deficiencies Are Common in Patients with Transfusion-dependent Thalassemia and Associated with Iron Overload

Patients with thalassemia are frequently deficient in key micronutrients. Attempts to correct these inadequacies through nutritional supplementation have been met…

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Prenatal and Preimplantation Diagnosis of Hemoglobinopathies

The hemoglobinopathies, as a group, are one of the most common serious monogenic diseases in the world. An accepted and…

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Hemanext® Inc. Receives CE Mark Certification For Innovative Red Blood Cell (RBC) Processing & Storage System

Hemanext Inc. announced today it has received a CE Certificate of Conformity for the CE Mark for its Hemanext ONE…

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