Catherine Skari
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Sep- 2026 -9 SeptemberScientific Literature
Transforming The Treatment of Alpha-Thalassemia: A Single-Center Retrospective Study on Hematopoietic Stem Cell Transplantation in Transfusion-Dependent Pediatric Patients
Abstract Hematopoietic stem cell transplantation (HSCT) is the only definitive cure for transfusion-dependent α-thalassemia, though comprehensive studies on its effectiveness…
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9 SeptemberScientific Literature
Disease-Related Complications and Risk Factors in Hemoglobin H Disease in a Thai Multicentre Registry
Abstract Hemoglobin H (Hb H) disease is a prevalent hereditary hemolytic anemia worldwide. Clinical severity varies by genotype, particularly between…
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9 SeptemberScientific Literature
Base Editing of HBG1 and HBG2 Promoters for Sickle Cell Disease
BACKGROUND Sickle cell disease is characterized by chronic hemolytic anemia and recurrent severe vaso-occlusive crises. Ristoglogene autogetemcel (risto-cel) includes autologous…
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9 SeptemberScientific Literature
Daily Zinc Supplementation for Infection Prevention in Children With Sickle Cell Anemia: The ZIPS-2 Randomized Clinical Trial
Abstract Importance: Despite existing prevention strategies, infections remain a major cause of morbidity and mortality in children in Africa with sickle…
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9 SeptemberScientific Literature
Contemporary Global Burden of Sickle Cell Anaemia Under-5 and Under-20: A Systematic Review and Meta-Analysis
Abstract Sickle cell disease (SCD), a prevalent inherited non-communicable disease, remains a neglected public health priority, especially among children and…
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9 SeptemberScientific Literature
Gene Therapy for Sickle Cell Disease: Practice Recommendations from the American Society for Transplantation and Cellular Therapy and the International Society for Cell & Gene Therapy
Abstract Gene therapy has emerged as a transformative treatment option for individuals with sickle cell disease (SCD), with recent regulatory…
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9 SeptemberScientific Literature
Osteoporosis Risk in Alpha and Beta Thalassemia: An Age- and Sex-Specific Retrospective Cohort Study
Abstract Summary Rationale: Differential skeletal risks between alpha- and beta-thalassemia subtypes remain unclear. Main result: Beta-thalassemia correlates with higher fracture…
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9 SeptemberScientific Literature
Addressing Obstetric and Gynecologic Needs in Thalassemia
Abstract Thalassemia represents a spectrum of rare, inherited blood disorders associated with a range of disease- and treatment-related complications. Thalassemia…
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9 SeptemberScientific Literature
Diagnosis and Management of Transfusion-Dependent Thalassemia: Evidence-Based Guidelines From the Pediatric Hematology Oncology Chapter of the Indian Academy of Pediatrics
Justification India bears a high burden of thalassemia, underscoring the need for enhanced awareness, systematic screening, and standardized, high-quality care.…
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8 SeptemberScientific Literature
Short- and Long-Term Effects of Transfusion in Β-Thalassemia: A Longitudinal Study of Transfusion Efficiency Factors
Abstract The complex interplay between donor and recipient factors likely influences transfusion outcomes in transfusion-dependent thalassemia (TDT). We investigated physiological…
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