Publications
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A Cross-Sectional, Multicenter, Disease-Specific, Health-Related Quality of Life study in Greek Transfusion Dependent Thalassemia Patients
The assessment of Health-Related Quality of Life (HRQoL) in Thalassemia offers a holistic approach to the disease and facilitates better communication between physicians and patients. This study aimed to evaluate…
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Economic and Clinical Burden of Managing Transfusion-Dependent b-Thalassemia in the United States
Aims To describe clinical complications, treatment use, healthcare resource utilization (HCRU), and costs among patients with transfusion-dependent β-thalassemia (TDT) in the United States. Materials and methods Merative MarketScan Databases were…
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Erythropoiesis in Lower-risk Myelodysplastic Syndromes and Beta Thalassemia
The hematologic disorders myelodysplastic syndromes and beta-thalassemia are characterized by ineffective erythropoiesis and anemia, often managed with regular blood transfusions. Erythropoiesis, the process by which sufficient numbers of functional erythrocytes are produced from hematopoietic…
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Association of Osteoporosis and Sarcopenia with Fracture Risk in Transfusion-Dependent Thalassemia
Patients with transfusion-dependent thalassaemia (TDT) have an increased risk of osteoporosis and fractures. They also have several potential factors associated with sarcopenia. There has been currently no study on sarcopenia…
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Lung Function Decline in Children with Sickle Cell Disease Treated with Hydroxyurea
Sickle cell disease (SCD), the most common form of an inherited hematological disorder, is caused by a genetic variant that leads to the synthesis of an abnormal haemoglobin, HbS. Deoxygenated…
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Nutrition in Thalassemia & PKD: A Guideline for Clinicians (2023)
A comprehensive publication on nutrition in two inherited haemolytic anaemias; thalassaemia and PKD, aimed at offering a critical review of existing knowledge, benefiting both haematologists and dietitians in managing patients…
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Splenectomy Significantly Associated with Thrombosis but Not with Pulmonary Hypertension in Patients with Transfusion-Dependent Thalassemia: A Meta-analysis of Observational Studies
Introduction: Thromboembolism (TE) and pulmonary hypertension (PH) constitute frequently occurring complications in patients with transfusion-dependent thalassemia and have been associated with splenectomy in different studies. Nevertheless, the size of the…
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Deferiprone vs Deferoxamine for Transfusional Iron Overload in Sickle Cell Disease and Other Anemias: Pediatric Subgroup Analysis of the Randomized, Open-label FIRST Study
Background: Children with sickle cell disease (SCD) who are chronically transfused often, require iron chelation therapy. There are limited data that allow for comparison of the efficacy and safety of…
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Guidelines for the Management of α-Thalassaemia (2023)
The first-ever Guidelines for the Management of α-thalassaemia serve as an indispensable resource for healthcare professionals, researchers, and others involved in the care of individuals with this complex, genetic blood…
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Pneumococcal Infections in Children with Sickle Cell Disease Before and After Pneumococcal Conjugate Vaccines
Children with sickle cell disease (SCD) are at increased risk of invasive pneumococcal infections (IPD). Over 25 years the Georgia Emerging Infections Program/CDC Active Bacterial Core Surveillance network identified 104…
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