Catherine Skari
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Jul- 2024 -26 JulyScientific Literature
Iron Chelation Therapy for Children with Transfusion‐Dependent β‐Thalassemia: How Young Is Too Young?
In this review, we provide a summary of evidence on iron overload in young children with transfusion-dependent β-thalassemia (TDT) and…
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25 JulyScientific Literature
Bone Health Impairment in Patients with Hemoglobinopathies: From Biological Bases to New Possible Therapeutic Strategies
Hemoglobinopathies are monogenic disorders affecting hemoglobin synthesis. Thalassemia and sickle cell disease (SCD) are considered the two major hemoglobinopathies. Thalassemia…
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25 JulyScientific Literature
Early Detection of Renal Complication in Children With Sickle Cell Disease: A Single Center Prospective Study
Introduction: This observational cross-sectional study aimed to identify predictors of renal complications in pediatric patients with sickle cell disease (SCD)…
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25 JulyScientific Literature
Hoping for a Normal Life: Decision‐Making on Hematopoietic Stem Cell Transplantation by Patients With a Hemoglobinopathy and Their Caregivers
Background: To provide insight into the perspectives of children and young adults with transfusion-dependent thalassemia and sickle cell disease and…
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25 JulyScientific Literature
Liver Disease in Patients With Transfusion-Dependent β-Thalassemia: The Emerging Role of Metabolism Dysfunction-Associated Steatotic Liver Disease
In this Editorial, we highlight the possible role that metabolism dysfunction-associated steatotic liver disease (MASLD) may play in the future,…
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25 JulyScientific Literature
Global Longitudinal Strain by Cardiac Magnetic Resonance Associated With Cardiac Iron and Complications in β-Thalassemia Major Patients
Background: The aim of this cross-sectional study was to investigate the association of left ventricular (LV) strain parameters with demographics,…
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25 JulyScientific Literature
Revisiting Iron Overload Status and Change Thresholds as Predictors of Mortality in Transfusion-Dependent β-Thalassemia: A 10-year Cohort Study
Data on iron overload status and change thresholds that can predict mortality in patients with transfusion-dependent β-thalassemia (TDT) are limited.…
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25 JulyScientific Literature
Global, Regional, and National Burden of Thalassemia, 1990–2021: A Systematic Analysis for the Global Burden of Disease
Background: Anemia is a significant contributor to the global disease burden, of which thalassemia is the most common hereditary anaemic…
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25 JulyScientific Literature
Growth and Endocrinopathies Among Children with β-Thalassemia Major Treated at Dubai Thalassemia Centre
Background: β-Thalassemia major (BTM) is one of the most common hereditary anemias worldwide. Patients suffer from iron overload that results…
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25 JulyScientific Literature
Novel Therapeutic Approaches in Thalassemias, Sickle Cell Disease and Other Red Cell Disorders
In this last decade, a deeper understanding of the pathophysiology of hereditary red cell disorders and the development of novel…
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