Catherine Skari – Page 39

Mar- 2020 -

26 March

The Changing Epidemiology of the Ageing Thalassaemia Populations: A Position Statement of the Thalassaemia International Federation

Therapeutic advances in β-thalassaemia have gradually lead to a significant improvement in prognosis over the past few decades. As a…

Feb- 2020 -

27 February

Scientific Literature

Sickle Cell Pain Crisis: Clinical Guidelines for the Use of Oxygen

Nocturnal hypoxemia is a prelude to vaso‐occlusive crisis (VOC). Vascular occlusion and disruption of tissue oxygenation are a prequel to…

12 February

Scientific Literature

Editing a γ-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes

Sickle cell disease (SCD) is caused by a single amino acid change in the adult hemoglobin (Hb) β-chain that causes…

Oct- 2019 -

29 October

Scientific Literature

Management of Age-associated Medical Complications in Patients with β-Thalassemia

Introduction: β-Thalassemia syndromes are among the most common monogenic disorders worldwide. Clinically, on the basis of the severity of the…

Sep- 2019 -

6 September

Scientific Literature

Challenges of Blood Transfusions in β-Thalassemia

Patients with β-thalassemia major (BTM) require regular blood transfusions, supported by appropriate iron chelation therapy (ICT), throughout their life. β-thalassemia is a global…

Jun- 2019 -

25 June

Scientific Literature

Understanding the Complications of Sickle Cell Disease

Sickle cell disease (SCD) is an autosomal recessive genetic condition that alters the shape and function of the hemoglobin molecule…

12 June

Scientific Literature

Innovative Curative Treatment of Beta-Thalassemia: Cost-efficacy Analysis of Gene Therapy Versus Allogenic Hematopoietic Stem Cell Transplantation

Seventy-five percent of patients with beta thalassemia (β-thalassemia) do not have human leukocyte antigen–matched siblings and until recently had no…

6 June

Scientific Literature