Scientific News
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Imatinib’s Impact on Reducing Painful Episodes in Sickle Cell Disease
Currently, hydroxyurea (HU) is the only FDA-approved drug highly recommended for treating sickle cell anemia. However, its efficiency varies among patients with sickle cell disease for unknown reasons. Given the…
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Corticosteroid Use in Pregnant Women with SCD Doubles Risk of Severe VOCs
According to a French study, corticosteroids used during pregnancy are a risk factor for more severe vaso-occlusive crises (VOCs) in women with sickle cell disease (SCD). This risk was especially…
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The Hidden Dangers of Sickle Cell Trait: Unraveling the Risk for Complications
Worldwide, it is estimated that there are 300 million people with sickle cell trait and one-third of this number are in sub-Saharan Africa. With these staggering figures, sickle cell disease…
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Transfusion-Dependent Thalassaemia Patients Display Mild COVID-19, Weakened Antibody Response
In a recent research published in the journal Cureus, patients with transfusion-dependent thalassaemia (TDT) were shown to have moderate or asymptomatic COVID-19 manifestations. Patients with TDT had an immunoglobulin G…
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Scientists Develop Safer Method for Gene-Editing Therapy Delivery
Researchers have found a new method of delivering gene-editing medicines to persons with blood illnesses such as thalassaemia and sickle cell disease (SCD), which if used in the clinic might…
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Deferiprone Reduces Iron Overload in Young Patients With Transfusion-Dependent Beta-Thalassaemia
In young patients with transfusion-dependent beta-thalassaemia (TDT), the use of early-start deferiprone appeared to be well tolerated and was associated with efficacy in reducing iron overload, according to the results…
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Epidemiology of Clinically Significant Forms of Alpha- and Beta Thalassemia: A Global Map of Evidence and Gaps
This systematic study looked at the worldwide and birth prevalence of clinically relevant types of alpha- and beta-thalassaemia. Searches were conducted in Embase, MEDLINE, and the Cochrane Library for observational…
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Sickle Cell Disease Is 11 Times More Deadly Than Previously Recorded, Suggests Study
A new study suggests the number of deaths due to sickle cell disease is 11 times higher than what is indicated from mortality data sources alone. Sickle cell disease is…
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Examining Mental Health, Education, Employment, and Pain in Sickle Cell Disease
Pain affects sickle cell disease (SCD) patients’ quality of life and functional ability. Βut what is the association of educational attainment, employment status, and mental health with pain episode frequency…
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NHS to Deliver World-First Blood-Matching Test to Aid Thalassemia and SCD Patients
National Health Services (NHS) of England is likely to introduce the world’s first genotyping blood test which could help ease the suffering of patients with thalassaemia, as donated blood poses…
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