Publications
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Innovative Curative Treatment of Beta-Thalassemia: Cost-efficacy Analysis of Gene Therapy Versus Allogenic Hematopoietic Stem Cell Transplantation
Seventy-five percent of patients with beta thalassemia (β-thalassemia) do not have human leukocyte antigen–matched siblings and until recently had no access to a curative treatment. Gene therapy is a promising…
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Need for a Universal Thalassemia Screening Programme in India? A Public Health Perspective
Thalassemia is one of the significant public health concerns as the carrier rate and disease numbers are increasing worldwide. The increase in number is because of consanguineous marriage which has…
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Hepatocellular Carcinoma in β-Thalassemia Patients: Review of the Literature with Molecular Insight into Liver Carcinogenesis
With the continuing progress in managing patients with thalassemia, especially in the setting of iron overload and iron chelation, the life span of these patients is increasing, while concomitantly increasing…
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Nutritional Deficiencies Are Common in Patients with Transfusion-dependent Thalassemia and Associated with Iron Overload
Patients with thalassemia are frequently deficient in key micronutrients. Attempts to correct these inadequacies through nutritional supplementation have been met with some success, although disparities between intake and circulating levels…
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Prenatal and Preimplantation Diagnosis of Hemoglobinopathies
The hemoglobinopathies, as a group, are one of the most common serious monogenic diseases in the world. An accepted and widely adopted approach to reduce the number of new cases…
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Potentially Curative Approaches for β-Thalassaemia (2021)
A comprehensive infographic with a head-to-head comparison on the most essential aspects of BMT, Gene Therapy & Gene Editing as potentially curative procedures for patients with β-thalassaemia.
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Explaining Gene Therapy in Thalassaemia (2020)
The second educational brochure from the TIF’s ‘Gene Therapy’ booklet series, providing an in-depth view of how this revolutionary therapy works in patients with β-thalassaemia major.
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Prevention of Inherited Diseases – The Example of β-Thalassaemia (2020)
An educational brochure explaining the inheritance patterns of β-thalassaemia and the choices available for an ”at-risk” couple to have a child without the disease.
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COVID-19 & Haemoglobin Disorders: Compilation of Information for Sickle Cell Disease (2020)
This document compiles information about the coronavirus pandemic specifically addressed to patients with sickle cell disease (SCD).
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COVID-19 & Haemoglobin Disorders: A Classification of Risk Groups & Other Considerations (2020)
A document seeking to offer a risk level classification for thalassaemia and SCD patients in relation to the ongoing COVID-19 pandemic.
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