Publications
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Nutrition in Thalassemia & PKD: A Guideline for Clinicians (2023)
A comprehensive publication on nutrition in two inherited haemolytic anaemias; thalassaemia and PKD, aimed at offering a critical review of existing knowledge, benefiting both haematologists and dietitians in managing patients…
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Splenectomy Significantly Associated with Thrombosis but Not with Pulmonary Hypertension in Patients with Transfusion-Dependent Thalassemia: A Meta-analysis of Observational Studies
Introduction: Thromboembolism (TE) and pulmonary hypertension (PH) constitute frequently occurring complications in patients with transfusion-dependent thalassemia and have been associated with splenectomy in different studies. Nevertheless, the size of the…
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Deferiprone vs Deferoxamine for Transfusional Iron Overload in Sickle Cell Disease and Other Anemias: Pediatric Subgroup Analysis of the Randomized, Open-label FIRST Study
Background: Children with sickle cell disease (SCD) who are chronically transfused often, require iron chelation therapy. There are limited data that allow for comparison of the efficacy and safety of…
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Guidelines for the Management of α-Thalassaemia (2023)
The first-ever Guidelines for the Management of α-thalassaemia serve as an indispensable resource for healthcare professionals, researchers, and others involved in the care of individuals with this complex, genetic blood…
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Pneumococcal Infections in Children with Sickle Cell Disease Before and After Pneumococcal Conjugate Vaccines
Children with sickle cell disease (SCD) are at increased risk of invasive pneumococcal infections (IPD). Over 25 years the Georgia Emerging Infections Program/CDC Active Bacterial Core Surveillance network identified 104…
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Impact of Imatinib on Reducing the Painful Crisis in Patients with Sickle Cell Disease
Introduction: Sickle cell disease (SCD) is a common hemoglobinopathy worldwide that causes painful crises and hospitalization of patients. These attacks decrease survival and cause chronic end-organ damage in these patients. Hypothesis: For this reason,…
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Health-Related Quality-of-Life Profile of Pediatric Patients with β-Thalassemia after Hematopoietic Stem Cell Transplantation
Matched hematopoietic stem cell transplantation (HSCT) is a feasible and curative treatment in pediatric patients with beta thalassemia major (β-TM). However, little data are available regarding patients and their parents’…
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Modelling the Public Health Impact of Voxelotor in the Management of Sickle Cell Disease in France
Sickle cell disease (SCD) is an inherited blood disorder in which sickle hemoglobin (HbS) polymerizes, leading to red blood cell sickling and chronic hemolytic anemia, vaso-occlusive crises, and end-organ damage…
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The Danish National Haemoglobinopathy Screening Programme: Report From 16 Years of Screening in a Low-prevalence, Non-endemic Region
The Danish national haemoglobinopathy screening programme seeks to determine parental haemoglobinopathy carrier state antenatally. In this retrospective register based study, we evaluated the 16-year trajectory of this programme, utilising the…
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Analysis of the Pregnancy Status and Outcomes of Pregnant Women with α-Thalassemia: A Retrospective Clinical Study
Background: The prevalence of α-thalassemia is high in Guangxi, and its co-occurrence with pregnancy may impede maternal system functions, with a consequent adverse effect on pregnancy progression and birth outcomes.…
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