Scientific News
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Sickle Cell Disease Is 11 Times More Deadly Than Previously Recorded, Suggests Study
A new study suggests the number of deaths due to sickle cell disease is 11 times higher than what is indicated from mortality data sources alone. Sickle cell disease is…
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Examining Mental Health, Education, Employment, and Pain in Sickle Cell Disease
Pain affects sickle cell disease (SCD) patients’ quality of life and functional ability. Βut what is the association of educational attainment, employment status, and mental health with pain episode frequency…
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NHS to Deliver World-First Blood-Matching Test to Aid Thalassemia and SCD Patients
National Health Services (NHS) of England is likely to introduce the world’s first genotyping blood test which could help ease the suffering of patients with thalassaemia, as donated blood poses…
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Health-related Quality of Life in Patients with β-Thalassemia: Data from the Phase 3 BELIEVE Trial of Luspatercept
The effects of anemia and fatigue, together with the effects of treatment regimens (i.e., RBCTs and iron chelation therapy) can have a considerable impact on the health-related quality of life…
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Treating Chronic Pain in Sickle Cell Disease
Chronic pain in sickle cell disease (SCD) refers to pain being present most of the days and lasting over three months. Although the pathophysiology of pain is not well described,…
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Gene Therapy for β-Hemoglobinopathies: From Discovery to Clinical Trials
Beta thalassaemia is an inherited disorder that impairs the production of haemoglobin, the blood protein responsible for transporting oxygen. Patients with beta thalassemia need regular blood transfusions to replace the…
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Increased Risk of Venous Thromboembolism in Splenectomized Patients with Sickle Cell Disease
Sickle cell disease (SCD) patients may need to have their spleen removed due to various conditions related to their health status (acute splenic sequestration crisis, hypersplenism, massive splenic infarction, splenic…
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Expecting More: The Case for Incorporating Fertility Services into Comprehensive Sickle Cell Disease Care
In recent years, advances in the medical care of sickle cell disease including optimal blood transfusion, the use of hydroxyurea and newer disease-modifying agents, as well as proper antibiotic prophylaxis…
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A Novel, Effective, and Efficient Strategy for Treating Sickle Cell Vaso-occlusive Events in the Infusion Center Setting
Coagulation factors are proteins in our blood, and they help form blood clots to stop bleeding when is needed. There are several types of coagulation factors that are all important…
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Splenectomy in Sickle Cell Disease: Do Benefits Outweigh Risks?
Spleen is an organ in the abdomen that plays an important role in immune system being a key-role organ in fighting any germs in the blood, filters the blood, stores…
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