Global Thalassaemia Review
Introduction
The first-ever TIF-developed Global Review of Thalassaemia!
The Global Thalassaemia Review was put together by TIF, in collaboration with the World Health Organisation (WHO), as a collection of independent reports to document the existing situation with thalassaemia across the world in the context of the various components of public health, clinical, and social services, which are deemed essential for patients’ survival and wellbeing.
This video briefly introduces the Review’s key objectives and findings, highlighting the huge heterogeneity and inequality that people affected by thalassaemia still encounter in terms of access to quality healthcare services in many countries across the world.
Explore the Report
The 2025 edition of the Global Thalassaemia Review (GTR), published by the Thalassaemia International Federation (TIF), represents the 5th edition of this landmark publication, offering an expanded and updated overview of the global landscape of thalassaemia prevention, control, and clinical management across more than 70 countries where the disease is prevalent.
Building on the strong foundation of previous editions, the GTR 2025 provides comprehensive, evidence-based information, covering key areas that shape the lives and health outcomes of people living with thalassaemia. These include prevention programmes, clinical management practices, blood safety, and health system responses, as well as the disease’s economic and social burden, including the cost of care and broader social determinants of health.
In addition, the Review includes significant updates to existing chapters and expanded analyses, particularly regarding the epidemiology and global distribution of thalassaemia, offering deeper insights into emerging trends and evolving healthcare needs across regions worldwide.
Contents
Regional Profiles
Additional Material
Milestones in Thalassaemia Treatment
by Prof John Porter
