Scientific Literature
Beta Thalassemia: Monitoring and New Treatment Approaches
Khandros, E., and Janet L. K. Hematology/Oncology Clinics 33, no. 3 (2019): 339-353. (2019)
Beta thalassemias represent a class of disorders with a high global prevalence and significant health and economic impact. Since the elucidation of the molecular mechanism in the 1960s, there has been significant progress in treatment of disease complications. With increasing use of transfusion therapy, iron overload has become a pressing problem, and chelation therapy is a key component of treatment.
The first part of this review focuses on monitoring of disease complications, transfusion therapy, iron overload, and chelator toxicity. In the second part, the authors review new developments in therapy for beta thalassemia.
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