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Apotransferrin

 

Update: 25 November 2019

No update available.

 

Update: 27 September 2019

No update available

 

Update: 30 July 2019

No update available.

 

Update: 30 May 2019 

  • Apotransferrinhas a physiological role in the transportation and distribution of iron among the body organs.
  • Apotrasferrin has received orphan drug designation from EMA
  • A proof of concept study in the Netherlands will begin in the second half of 2019 lasting 16 weeks with a maximum of 12 patients. Participants will receive apotrasferrin every two weeks to evaluate efficacy and safety in the treatment of patients with β-thalassaemia intermedia and analyse the impact of iron homeostasis and red blood cell function.
  • The study expects to show that apotrasferrin treatment will reduce hemolysis and iron overload as well as extra-medullar hematopoiesis.

Sources:

https://www.sanquin.org/news/2019/apr/clinical-trial-apotransferrin-treatment-in-patients-with-beta-thalassemia